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Bioinformatic and Mechanistic Analysis of the Palmerolide PKS-NRPS Biosynthetic Pathway From the Microbiome of an Antarctic Ascidian

Complex interactions exist between microbiomes and their hosts. Increasingly, defensive metabolites that have been attributed to host biosynthetic capability are now being recognized as products of host-associated microbes. These unique metabolites often have bioactivity targets in human disease and...

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Detalles Bibliográficos
Autores principales: Avalon, Nicole E., Murray, Alison E., Daligault, Hajnalka E., Lo, Chien-Chi, Davenport, Karen W., Dichosa, Armand E. K., Chain, Patrick S. G., Baker, Bill J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739492/
https://www.ncbi.nlm.nih.gov/pubmed/35004620
http://dx.doi.org/10.3389/fchem.2021.802574