Retinoblastoma protein regulates carcinogen susceptibility at heterochromatic cancer driver loci

Carcinogenic insult, such as UV light exposure, creates DNA lesions that evolve into mutations if left unrepaired. These resulting mutations can contribute to carcinogenesis and drive malignant phenotypes. Susceptibility to carcinogens (i.e., the propensity to form a carcinogen-induced DNA lesion) i...

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Detalles Bibliográficos
Autores principales: Wong, Ka Man, King, Devin A, Schwartz, Erin K, Herrera, Rafael E, Morrison, Ashby J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739494/
https://www.ncbi.nlm.nih.gov/pubmed/34983823
http://dx.doi.org/10.26508/lsa.202101134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739494/
https://www.ncbi.nlm.nih.gov/pubmed/34983823
http://dx.doi.org/10.26508/lsa.202101134

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