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ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway

The RNA-sensing signaling pathway has been well studied as an essential antiviral mechanism of innate immunity. However, its role in non-infected cells is yet to be thoroughly characterized. Here, we demonstrated that the RNA sensing signaling pathway also reacts to the endogenous cellular RNAs in e...

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Detalles Bibliográficos
Autores principales: Guo, Xinfeng, Liu, Silvia, Yan, Rose, Nguyen, Vy, Zenati, Mazen, Billiar, Timothy R, Wang, Qingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739526/
https://www.ncbi.nlm.nih.gov/pubmed/34969816
http://dx.doi.org/10.26508/lsa.202101191