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Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law

Alternative splicing is ubiquitous, but the mechanisms underlying its pattern of evolutionary divergence across mammalian tissues are still underexplored. Here, we investigated the cis-regulatory divergences and their relationship with tissue-dependent trans-regulation in multiple tissues of an F1 h...

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Detalles Bibliográficos
Autores principales: Zou, Xudong, Schaefke, Bernhard, Li, Yisheng, Jia, Fujian, Sun, Wei, Li, Guipeng, Liang, Weizheng, Reif, Tristan, Heyd, Florian, Gao, Qingsong, Tian, Shuye, Li, Yanping, Tang, Yisen, Fang, Liang, Hu, Yuhui, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739531/
https://www.ncbi.nlm.nih.gov/pubmed/34969779
http://dx.doi.org/10.26508/lsa.202101333