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Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

BACKGROUND: Impaired lung function is predictive of mortality and is a key component of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure to air pollution, but the effect of their interactions...

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Detalles Bibliográficos
Autores principales: Melbourne, Carl A., Mesut Erzurumluoglu, A., Shrine, Nick, Chen, Jing, Tobin, Martin D., Hansell, Anna L., Wain, Louise V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739564/
https://www.ncbi.nlm.nih.gov/pubmed/34923368
http://dx.doi.org/10.1016/j.envint.2021.107041