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Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals
BACKGROUND: Impaired lung function is predictive of mortality and is a key component of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure to air pollution, but the effect of their interactions...
Autores principales: | Melbourne, Carl A., Mesut Erzurumluoglu, A., Shrine, Nick, Chen, Jing, Tobin, Martin D., Hansell, Anna L., Wain, Louise V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739564/ https://www.ncbi.nlm.nih.gov/pubmed/34923368 http://dx.doi.org/10.1016/j.envint.2021.107041 |
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