Effect of Inflammatory Signaling on Human Articular Chondrocyte Hypertrophy: Potential Involvement of Tissue Repair Macrophages

OBJECTIVE: In osteoarthritis, chondrocytes tend to acquire a hypertrophic phenotype, which contributes to the modification of the extracellular matrix, resulting in permanent cartilage changes. In mouse chondrocytes, pro-inflammatory macrophages and pro-inflammatory cytokines have been shown to stim...

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Detalles Bibliográficos
Autores principales: Ferrao Blanco, Mauricio N., Bastiaansen-Jenniskens, Yvonne M., Chambers, Mark G., Pitsillides, Andrew A., Narcisi, Roberto, van Osch, Gerjo J.V.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Clinical Research papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739598/
https://www.ncbi.nlm.nih.gov/pubmed/34165367
http://dx.doi.org/10.1177/19476035211021907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739598/
https://www.ncbi.nlm.nih.gov/pubmed/34165367
http://dx.doi.org/10.1177/19476035211021907

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