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Effect of Inflammatory Signaling on Human Articular Chondrocyte Hypertrophy: Potential Involvement of Tissue Repair Macrophages
OBJECTIVE: In osteoarthritis, chondrocytes tend to acquire a hypertrophic phenotype, which contributes to the modification of the extracellular matrix, resulting in permanent cartilage changes. In mouse chondrocytes, pro-inflammatory macrophages and pro-inflammatory cytokines have been shown to stim...
Autores principales: | Ferrao Blanco, Mauricio N., Bastiaansen-Jenniskens, Yvonne M., Chambers, Mark G., Pitsillides, Andrew A., Narcisi, Roberto, van Osch, Gerjo J.V.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739598/ https://www.ncbi.nlm.nih.gov/pubmed/34165367 http://dx.doi.org/10.1177/19476035211021907 |
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