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Anti-inflammatory role of GM1 and other gangliosides on microglia

BACKGROUND: Gangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects in the ganglioside biosynthetic pathway result in severe neurodegenerative diseases, while a partial decrease in the...

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Detalles Bibliográficos
Autores principales: Galleguillos, Danny, Wang, Qian, Steinberg, Noam, Zaidi, Asifa, Shrivastava, Gaurav, Dhami, Kamaldeep, Daskhan, Gour C., Schmidt, Edward N., Dworsky-Fried, Zoë, Giuliani, Fabrizio, Churchward, Matthew, Power, Christopher, Todd, Kathryn, Taylor, Anna, Macauley, Matthew S., Sipione, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739653/
https://www.ncbi.nlm.nih.gov/pubmed/34991625
http://dx.doi.org/10.1186/s12974-021-02374-x