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Functional characterization of 5′ UTR cis-acting sequence elements that modulate translational efficiency in Plasmodium falciparum and humans

BACKGROUND: The eukaryotic parasite Plasmodium falciparum causes millions of malarial infections annually while drug resistance to common anti-malarials is further confounding eradication efforts. Translation is an attractive therapeutic target that will benefit from a deeper mechanistic understandi...

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Detalles Bibliográficos
Autores principales: Garcia, Valentina E., Dial, Rebekah, DeRisi, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739713/
https://www.ncbi.nlm.nih.gov/pubmed/34991611
http://dx.doi.org/10.1186/s12936-021-04024-2