Cargando…

Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types

Recent studies have shown the significance of metabolic reprogramming in immune and stromal cell function. Yet, the metabolic reconfiguration of RA macrophages (MΦs) is incompletely understood during active disease and in crosstalk with other cell types in experimental arthritis. This study elucidat...

Descripción completa

Detalles Bibliográficos
Autores principales: Umar, Sadiq, Palasiewicz, Karol, Volin, Michael V., Romay, Bianca, Rahat, Rani, Tetali, Chandana, Arami, Shiva, Guma, Monica, Ascoli, Christian, Sweiss, Nadera, Zomorrodi, Ryan K, O’Neill, Luke A. J., Shahrara, Shiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739866/
https://www.ncbi.nlm.nih.gov/pubmed/34705053
http://dx.doi.org/10.1007/s00018-021-03978-5