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(Pro)renin Receptor Inhibition Reduces Plasma Cholesterol and Triglycerides but Does Not Attenuate Atherosclerosis in Atherosclerotic Mice

Objective: Elevated plasma cholesterol concentrations contributes to ischemic cardiovascular diseases. Recently, we showed that inhibiting hepatic (pro)renin receptor [(P)RR] attenuated diet-induced hypercholesterolemia and hypertriglyceridemia in low-density lipoprotein receptor (LDLR) deficient mi...

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Detalles Bibliográficos
Autores principales: Ye, Dien, Yang, Xiaofei, Ren, Liwei, Lu, Hong S., Sun, Yuan, Lin, Hui, Tan, Lunbo, Wang, Na, Nguyen, Genevieve, Bader, Michael, Mullick, Adam E., Danser, A. H. Jan, Daugherty, Alan, Jiang, Yizhou, Sun, Yidan, Li, Furong, Lu, Xifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739895/
https://www.ncbi.nlm.nih.gov/pubmed/35004870
http://dx.doi.org/10.3389/fcvm.2021.725203