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Long-Term Maintenance and Meiotic Entry of Early Germ Cells in Murine Testicular Organoids Functionalized by 3D Printed Scaffolds and Air-Medium Interface Cultivation

Short-term germ cell survival and central tissue degeneration limit organoid cultures. Here, testicular organoids (TOs) were generated from two different mouse strains in 3D printed one-layer scaffolds (1LS) at the air-medium interface displaying tubule-like structures and Leydig cell functionality...

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Detalles Bibliográficos
Autores principales: Richer, Guillaume, Hobbs, Robin M., Loveland, Katherine L., Goossens, Ellen, Baert, Yoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739976/
https://www.ncbi.nlm.nih.gov/pubmed/35002756
http://dx.doi.org/10.3389/fphys.2021.757565