HIF-1α Induces HECTD2 Up-Regulation and Aggravates the Malignant Progression of Renal Cell Cancer via Repressing miR-320a

Renal cell carcinoma (RCC) is a frequent malignancy of the urinary system. It has been found that hypoxia mediates the malignant evolvement of RCC. Here, we probe the impact and potential mechanism of HECT domain E3 ubiquitin-protein ligase 2 (HECTD2) and HIF-1α on regulating RCC evolvement. RCC tis...

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Detalles Bibliográficos
Autores principales: Lv, Dong, Shen, Taimin, Yao, Juncheng, Yang, Qi, Xiang, Ying, Ma, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739985/
https://www.ncbi.nlm.nih.gov/pubmed/35004677
http://dx.doi.org/10.3389/fcell.2021.775642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739985/
https://www.ncbi.nlm.nih.gov/pubmed/35004677
http://dx.doi.org/10.3389/fcell.2021.775642

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