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Maternal Glucose and LDL-Cholesterol Levels Are Related to Placental Leptin Gene Methylation, and, Together With Nutritional Factors, Largely Explain a Higher Methylation Level Among Ethnic South Asians

BACKGROUND: Leptin, mainly secreted by fat cells, plays a core role in the regulation of appetite and body weight, and has been proposed as a mediator of metabolic programming. During pregnancy leptin is also secreted by the placenta, as well as being a key regulatory cytokine for the development, h...

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Detalles Bibliográficos
Autores principales: Sletner, Line, Moen, Aina E. F., Yajnik, Chittaranjan S., Lekanova, Nadezhda, Sommer, Christine, Birkeland, Kåre I., Jenum, Anne K., Böttcher, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739998/
https://www.ncbi.nlm.nih.gov/pubmed/35002980
http://dx.doi.org/10.3389/fendo.2021.809916