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High Expression of Glycolytic Genes in Clinical Glioblastoma Patients Correlates With Lower Survival

Glioblastoma (GBM), the most aggressive brain tumor, is associated with a median survival at diagnosis of 16–20 months and limited treatment options. The key hallmark of GBM is altered tumor metabolism and marked increase in the rate of glycolysis. Aerobic glycolysis along with elevated glucose cons...

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Detalles Bibliográficos
Autores principales: Stanke, Kimberly M, Wilson, Carrick, Kidambi, Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740031/
https://www.ncbi.nlm.nih.gov/pubmed/35004842
http://dx.doi.org/10.3389/fmolb.2021.752404