Digital gene expression analysis of NSCLC-patients reveals strong immune pressure, resulting in an immune escape under immunotherapy

BACKGROUND: Immune checkpoint inhibitors (ICIs) are currently one of the most promising therapy options in the field of oncology. Although the first pivotal ICI trial results were published in 2011, few biomarkers exist to predict their therapy outcome. PD-L1 expression and tumor mutational burden (...

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Detalles Bibliográficos
Autores principales: Wessolly, Michael, Stephan-Falkenau, Susann, Streubel, Anna, Wiesweg, Marcel, Borchert, Sabrina, Mairinger, Elena, Kollmeier, Jens, Reis, Henning, Bauer, Torsten, Schmid, Kurt Werner, Mairinger, Thomas, Schuler, Martin, Mairinger, Fabian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740040/
https://www.ncbi.nlm.nih.gov/pubmed/34996407
http://dx.doi.org/10.1186/s12885-021-09111-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740040/
https://www.ncbi.nlm.nih.gov/pubmed/34996407
http://dx.doi.org/10.1186/s12885-021-09111-w

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