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The CpG island methylator phenotype increases the risk of high-grade squamous intraepithelial lesions and cervical cancer
BACKGROUND: High-risk human papillomavirus (HR-HPV) infection is the main cause of cervical cancer, but additional alterations are necessary for its development. Abnormal DNA methylation has an important role in the origin and dissemination of cervical cancer and other human tumors. In this work, we...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740093/ https://www.ncbi.nlm.nih.gov/pubmed/34991696 http://dx.doi.org/10.1186/s13148-021-01224-0 |