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A living cell-based fluorescent reporter for high-throughput screening of anti-tumor drugs

Suppression of cellular O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) can repress proliferation and migration of various cancer cells, which opens a new avenue for cancer therapy. Based on the regulation of insulin gene transcription, we designed a cell-based fluorescent reporter capable of...

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Detalles Bibliográficos
Autores principales: Tang, Ningning, Li, Ling, Xie, Fei, Lu, Ying, Zuo, Zifan, Shan, Hao, Zhang, Quan, Zhang, Lianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740116/
https://www.ncbi.nlm.nih.gov/pubmed/35028187
http://dx.doi.org/10.1016/j.jpha.2021.04.001