Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels

Background: Similarities in the biology of pulmonary hypertension and cancer suggest that anticancer therapies, such as sanguinarine, may also be effective in treating pulmonary hypertension. This, along with underlying biochemical pathways, is investigated in this study. Methods: Rats were subjecte...

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Detalles Bibliográficos
Autores principales: Fan, Fenling, Zou, Yifan, Wang, Yousen, Zhang, Peng, Wang, Xiaoyu, Dart, Anthony M., Zou, Yuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740145/
https://www.ncbi.nlm.nih.gov/pubmed/35002707
http://dx.doi.org/10.3389/fphar.2021.768513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740145/
https://www.ncbi.nlm.nih.gov/pubmed/35002707
http://dx.doi.org/10.3389/fphar.2021.768513

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