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Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid

Given the important role of voltage-gated sodium (Na(V)) channel-modulating spider toxins in elucidating the function, pharmacology, and mechanism of action of therapeutically relevant Na(V) channels, we screened the venom from Australian theraphosid species against the human pain target hNa(V)1.7....

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Detalles Bibliográficos
Autores principales: Dongol, Yashad, Choi, Phil M., Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C., Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740163/
https://www.ncbi.nlm.nih.gov/pubmed/35002728
http://dx.doi.org/10.3389/fphar.2021.795455