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Latent Transforming Growth Factor-β Binding Protein-2 Regulates Lung Fibroblast-to-Myofibroblast Differentiation in Pulmonary Fibrosis via NF-κB Signaling

Despite past extensive studies, the mechanisms underlying pulmonary fibrosis (PF) still remain poorly understood. The aberrantly activated lung myofibroblasts, predominantly emerging through fibroblast-to-myofibroblast differentiation, are considered to be the key cells in PF, resulting in excessive...

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Detalles Bibliográficos
Autores principales: Zou, Menglin, Zou, Jingfeng, Hu, Xingxing, Zheng, Weishuai, Zhang, Mingyang, Cheng, Zhenshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740300/
https://www.ncbi.nlm.nih.gov/pubmed/35002722
http://dx.doi.org/10.3389/fphar.2021.788714