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A novel graph-based k-partitioning approach improves the detection of gene-gene correlations by single-cell RNA sequencing

BACKGROUND: Gene expression is regulated by transcription factors, cofactors, and epigenetic mechanisms. Coexpressed genes indicate similar functional categories and gene networks. Detecting gene-gene coexpression is important for understanding the underlying mechanisms of cellular function and huma...

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Detalles Bibliográficos
Autores principales: Xu, Heng, Hu, Ying, Zhang, Xinyu, Aouizerat, Bradley E., Yan, Chunhua, Xu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740455/
https://www.ncbi.nlm.nih.gov/pubmed/34996359
http://dx.doi.org/10.1186/s12864-021-08235-4