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A novel graph-based k-partitioning approach improves the detection of gene-gene correlations by single-cell RNA sequencing
BACKGROUND: Gene expression is regulated by transcription factors, cofactors, and epigenetic mechanisms. Coexpressed genes indicate similar functional categories and gene networks. Detecting gene-gene coexpression is important for understanding the underlying mechanisms of cellular function and huma...
Autores principales: | Xu, Heng, Hu, Ying, Zhang, Xinyu, Aouizerat, Bradley E., Yan, Chunhua, Xu, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740455/ https://www.ncbi.nlm.nih.gov/pubmed/34996359 http://dx.doi.org/10.1186/s12864-021-08235-4 |
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