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Microbial pathogens induce neurodegeneration in Alzheimer’s disease mice: protection by microglial regulation
BACKGROUND: Neurodegeneration is considered the consequence of misfolded proteins’ deposition. Little is known about external environmental effects on the neurodegenerative process. Infectious agent-derived pathogen-associated molecular patterns (PAMPs) activate microglia, key players in neurodegene...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740456/ https://www.ncbi.nlm.nih.gov/pubmed/34991645 http://dx.doi.org/10.1186/s12974-021-02369-8 |