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Microbial pathogens induce neurodegeneration in Alzheimer’s disease mice: protection by microglial regulation

BACKGROUND: Neurodegeneration is considered the consequence of misfolded proteins’ deposition. Little is known about external environmental effects on the neurodegenerative process. Infectious agent-derived pathogen-associated molecular patterns (PAMPs) activate microglia, key players in neurodegene...

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Detalles Bibliográficos
Autores principales: Ganz, Tal, Fainstein, Nina, Elad, Amit, Lachish, Marva, Goldfarb, Smadar, Einstein, Ofira, Ben-Hur, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740456/
https://www.ncbi.nlm.nih.gov/pubmed/34991645
http://dx.doi.org/10.1186/s12974-021-02369-8