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Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP

BACKGROUND: Interferon regulatory factor-8 (IRF8) and nuclear factor-activated T cells c1 (NFATc1) are two transcription factors that have an important role in osteoclast differentiation. Thanks to ChIP-seq technology, scientists can now estimate potential genome-wide target genes of IRF8 and NFATc1...

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Detalles Bibliográficos
Autores principales: Wang, Honglin, Joshi, Pujan, Hong, Seung-Hyun, Maye, Peter F., Rowe, David W., Shin, Dong-Guk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740472/
https://www.ncbi.nlm.nih.gov/pubmed/34991467
http://dx.doi.org/10.1186/s12864-021-08159-z