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Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA

Bipolar disorder (BD) is a severe psychiatric disorder characterized by repeated conflicting manic and depressive states. In addition to genetic factors, complex gene–environment interactions, which alter the epigenetic status in the brain, contribute to the etiology and pathophysiology of BD. Here,...

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Detalles Bibliográficos
Autores principales: Sugawara, Hiroko, Bundo, Miki, Kasahara, Takaoki, Nakachi, Yutaka, Ueda, Junko, Kubota-Sakashita, Mie, Iwamoto, Kazuya, Kato, Tadafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740475/
https://www.ncbi.nlm.nih.gov/pubmed/34991677
http://dx.doi.org/10.1186/s13041-021-00894-4