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Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA
Bipolar disorder (BD) is a severe psychiatric disorder characterized by repeated conflicting manic and depressive states. In addition to genetic factors, complex gene–environment interactions, which alter the epigenetic status in the brain, contribute to the etiology and pathophysiology of BD. Here,...
Autores principales: | Sugawara, Hiroko, Bundo, Miki, Kasahara, Takaoki, Nakachi, Yutaka, Ueda, Junko, Kubota-Sakashita, Mie, Iwamoto, Kazuya, Kato, Tadafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740475/ https://www.ncbi.nlm.nih.gov/pubmed/34991677 http://dx.doi.org/10.1186/s13041-021-00894-4 |
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