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T cell receptor beta germline variability is revealed by inference from repertoire data
BACKGROUND: T and B cell receptor (TCR, BCR) repertoires constitute the foundation of adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a common approach to study immune system dynamics. Understanding the genetic factors influencing the composition and dynamics of these...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740489/ https://www.ncbi.nlm.nih.gov/pubmed/34991709 http://dx.doi.org/10.1186/s13073-021-01008-4 |