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T cell receptor beta germline variability is revealed by inference from repertoire data

BACKGROUND: T and B cell receptor (TCR, BCR) repertoires constitute the foundation of adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a common approach to study immune system dynamics. Understanding the genetic factors influencing the composition and dynamics of these...

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Detalles Bibliográficos
Autores principales: Omer, Aviv, Peres, Ayelet, Rodriguez, Oscar L, Watson, Corey T, Lees, William, Polak, Pazit, Collins, Andrew M, Yaari, Gur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740489/
https://www.ncbi.nlm.nih.gov/pubmed/34991709
http://dx.doi.org/10.1186/s13073-021-01008-4