Structural and Functional Analyses of the Severe Acute Respiratory Syndrome Coronavirus Endoribonuclease Nsp15

The severe acute respiratory syndrome (SARS) coronavirus encodes several RNA-processing enzymes that are unusual for RNA viruses, including Nsp15 (nonstructural protein 15), a hexameric endoribonuclease that preferentially cleaves 3′ of uridines. We solved the structure of a catalytically inactive m...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Kanchan, Palaninathan, Satheesh, Alcantara, Joanna Maria Ortiz, Li Yi, Lillian, Guarino, Linda, Sacchettini, James C., Kao, C. Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2008
Materias:
RNA: Processing and Catalysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740563/
https://www.ncbi.nlm.nih.gov/pubmed/18045871
http://dx.doi.org/10.1074/jbc.M708375200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740563/
https://www.ncbi.nlm.nih.gov/pubmed/18045871
http://dx.doi.org/10.1074/jbc.M708375200

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