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Sod1 integrates oxygen availability to redox regulate NADPH production and the thiol redoxome
Cu/Zn superoxide dismutase (Sod1) is a highly conserved and abundant antioxidant enzyme that detoxifies superoxide (O(2)(•−)) by catalyzing its conversion to dioxygen (O(2)) and hydrogen peroxide (H(2)O(2)). Using Saccharomyces cerevisiae and mammalian cells, we discovered that a major aspect of the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740578/ https://www.ncbi.nlm.nih.gov/pubmed/34969852 http://dx.doi.org/10.1073/pnas.2023328119 |