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Identification of Two Critical Amino Acid Residues of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Its Variation in Zoonotic Tropism Transition via a Double Substitution Strategy

Severe acute respiratory syndrome coronavirus (SARS-CoV) is a recently identified human coronavirus. The extremely high homology of the viral genomic sequences between the viruses isolated from human (huSARS-CoV) and those of palm civet origin (pcSARS-CoV) suggested possible palm civet-to-human tran...

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Detalles Bibliográficos
Autores principales: Qu, Xiu-Xia, Hao, Pei, Song, Xi-Jun, Jiang, Si-Ming, Liu, Yan-Xia, Wang, Pei-Gang, Rao, Xi, Song, Huai-Dong, Wang, Sheng-Yue, Zuo, Yu, Zheng, Ai-Hua, Luo, Min, Wang, Hua-Lin, Deng, Fei, Wang, Han-Zhong, Hu, Zhi-Hong, Ding, Ming-Xiao, Zhao, Guo-Ping, Deng, Hong-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740630/
https://www.ncbi.nlm.nih.gov/pubmed/15980414
http://dx.doi.org/10.1074/jbc.M500662200