STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma

Airway remodeling and airway hyperresponsiveness are central drivers of asthma severity. Airway remodeling is a structural change involving the dedifferentiation of airway smooth muscle (ASM) cells from a quiescent to a proliferative and secretory phenotype. Here, we show up-regulation of the endopl...

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Detalles Bibliográficos
Autores principales: Johnson, Martin T., Xin, Ping, Benson, J. Cory, Pathak, Trayambak, Walter, Vonn, Emrich, Scott M., Yoast, Ryan E., Zhang, Xuexin, Cao, Gaoyuan, Panettieri, Reynold A., Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740694/
https://www.ncbi.nlm.nih.gov/pubmed/34949717
http://dx.doi.org/10.1073/pnas.2114557118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740694/
https://www.ncbi.nlm.nih.gov/pubmed/34949717
http://dx.doi.org/10.1073/pnas.2114557118

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