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BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4

Macrophages induce a number of inflammatory response genes in response to stimulation with microbial ligands. In response to endotoxin Lipid A, a gene-activation cascade of primary followed by secondary-response genes is induced. Epigenetic state is an important regulator of the kinetics, specificit...

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Detalles Bibliográficos
Autores principales: Ahmed, Nasiha S., Gatchalian, Jovylyn, Ho, Josephine, Burns, Mannix J., Hah, Nasun, Wei, Zong, Downes, Michael, Evans, Ronald M., Hargreaves, Diana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740701/
https://www.ncbi.nlm.nih.gov/pubmed/34983841
http://dx.doi.org/10.1073/pnas.2110812119