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BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4
Macrophages induce a number of inflammatory response genes in response to stimulation with microbial ligands. In response to endotoxin Lipid A, a gene-activation cascade of primary followed by secondary-response genes is induced. Epigenetic state is an important regulator of the kinetics, specificit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740701/ https://www.ncbi.nlm.nih.gov/pubmed/34983841 http://dx.doi.org/10.1073/pnas.2110812119 |