Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer

Brain metastases are a leading cause of death in patients with breast cancer. The lack of clinical trials and the presence of the blood–brain barrier limit therapeutic options. Furthermore, overexpression of the human epidermal growth factor receptor 2 (HER2) increases the incidence of breast cancer...

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Detalles Bibliográficos
Autores principales: Cordero, Alex, Ramsey, Matthew D., Kanojia, Deepak, Fares, Jawad, Petrosyan, Edgar, Schwartz, Charles W., Burga, Rachel, Zhang, Peng, Rashidi, Aida, Castro, Brandyn, Xiao, Ting, Lee-Chang, Catalina, Miska, Jason, Balyasnikova, Irina V., Ahmed, Atique U., Lesniak, Maciej S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740706/
https://www.ncbi.nlm.nih.gov/pubmed/34969858
http://dx.doi.org/10.1073/pnas.2112491119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740706/
https://www.ncbi.nlm.nih.gov/pubmed/34969858
http://dx.doi.org/10.1073/pnas.2112491119

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