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Flexibility of telomerase in binding the RNA template and DNA telomeric repeat

Telomerase synthesizes telomeres at the ends of linear chromosomes by repeated reverse transcription from a short RNA template. Crystal structures of Tribolium castaneum telomerase reverse transcriptase (tcTERT) and cryoelectron microscopy (cryo-EM) structures of human and Tetrahymena telomerase hav...

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Detalles Bibliográficos
Autores principales: Choi, Woo Suk, Weng, Peter J., Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740718/
https://www.ncbi.nlm.nih.gov/pubmed/34969861
http://dx.doi.org/10.1073/pnas.2116159118