Mechanistic analysis of carbon–carbon bond formation by deoxypodophyllotoxin synthase

Deoxypodophyllotoxin contains a core of four fused rings (A to D) with three consecutive chiral centers, the last being created by the attachment of a peripheral trimethoxyphenyl ring (E) to ring C. Previous studies have suggested that the iron(II)- and 2-oxoglutarate–dependent (Fe/2OG) oxygenase, d...

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Detalles Bibliográficos
Autores principales: Tang, Haoyu, Wu, Min-Hao, Lin, Hsiao-Yu, Han, Meng-Ru, Tu, Yueh-Hua, Yang, Zhi-Jie, Chien, Tun-Cheng, Chan, Nei-Li, Chang, Wei-chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740726/
https://www.ncbi.nlm.nih.gov/pubmed/34969844
http://dx.doi.org/10.1073/pnas.2113770119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740726/
https://www.ncbi.nlm.nih.gov/pubmed/34969844
http://dx.doi.org/10.1073/pnas.2113770119

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