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SARS-CoV-2 spike engagement of ACE2 primes S2′ site cleavage and fusion initiation

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in tremendous loss worldwide. Although viral spike (S) protein binding of angiotensin-converting enzyme 2 (ACE2) has been established, the functional consequences of the initial recept...

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Detalles Bibliográficos
Autores principales: Yu, Shi, Zheng, Xu, Zhou, Bingjie, Li, Juan, Chen, Mengdan, Deng, Rong, Wong, Gary, Lavillette, Dimitri, Meng, Guangxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740742/
https://www.ncbi.nlm.nih.gov/pubmed/34930824
http://dx.doi.org/10.1073/pnas.2111199119