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Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium

The clinical impact of rhinovirus C (RV-C) is well-documented; yet, the viral life cycle remains poorly defined. Thus, we characterized RV-C15 replication at the single-cell level and its impact on the human airway epithelium (HAE) using a physiologically-relevant in vitro model. RV-C15 replication...

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Detalles Bibliográficos
Autores principales: Gagliardi, Talita B., Goldstein, Monty E., Song, Daniel, Gray, Kelsey M., Jung, Jae W., Ignacio, Maxinne A., Stroka, Kimberly M., Duncan, Gregg A., Scull, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741012/
https://www.ncbi.nlm.nih.gov/pubmed/34995322
http://dx.doi.org/10.1371/journal.ppat.1010159