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Numerical approaches for the rapid analysis of prophylactic efficacy against HIV with arbitrary drug-dosing schemes

Pre-exposure prophylaxis (PrEP) is an important pillar to prevent HIV transmission. Because of experimental and clinical shortcomings, mathematical models that integrate pharmacological, viral- and host factors are frequently used to quantify clinical efficacy of PrEP. Stochastic simulations of thes...

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Detalles Bibliográficos
Autores principales: Zhang, Lanxin, Wang, Junyu, von Kleist, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741042/
https://www.ncbi.nlm.nih.gov/pubmed/34941864
http://dx.doi.org/10.1371/journal.pcbi.1009295