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Quantile-specific heritability of plasma fibrinogen concentrations

BACKGROUND: Fibrinogen is a moderately heritable blood protein showing different genetic effects by sex, race, smoking status, pollution exposure, and disease status. These interactions may be explained in part by “quantile-dependent expressivity”, where the effect size of a genetic variant depends...

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Detalles Bibliográficos
Autor principal: Williams, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741049/
https://www.ncbi.nlm.nih.gov/pubmed/34995330
http://dx.doi.org/10.1371/journal.pone.0262395