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Formimidoyltransferase cyclodeaminase prevents the starvation-induced liver hepatomegaly and dysfunction through downregulating mTORC1

The liver is a crucial center in the regulation of energy homeostasis under starvation. Although downregulation of mammalian target of rapamycin complex 1 (mTORC1) has been reported to play pivotal roles in the starvation responses, the underpinning mechanisms in particular upstream factors that dow...

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Detalles Bibliográficos
Autores principales: Zhang, Wenfeng, Wu, Chaoying, Ni, Rui, Yang, Qifen, Luo, Lingfei, He, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741050/
https://www.ncbi.nlm.nih.gov/pubmed/34941873
http://dx.doi.org/10.1371/journal.pgen.1009980