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A lethal mouse model for evaluating vaccine-associated enhanced respiratory disease during SARS-CoV-2 infection

One safety concern during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine development has been the vaccine-associated enhanced disease, which is characterized by eosinophilic immunopathology and T helper cell type 2 (T(H)2)–biased immune responses with insufficient neutralizing...

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Detalles Bibliográficos
Autores principales: Iwata-Yoshikawa, Naoko, Shiwa, Nozomi, Sekizuka, Tsuyoshi, Sano, Kaori, Ainai, Akira, Hemmi, Takuya, Kataoka, Michiyo, Kuroda, Makoto, Hasegawa, Hideki, Suzuki, Tadaki, Nagata, Noriyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741184/
https://www.ncbi.nlm.nih.gov/pubmed/34995117
http://dx.doi.org/10.1126/sciadv.abh3827