Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors

To date, effective therapeutic treatments that confer strong attenuation against coronaviruses (CoVs) remain elusive. Among potential drug targets, the helicase of CoVs is attractive due to its sequence conservation and indispensability. We rely on atomistic molecular dynamics simulations to explore...

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Detalles Bibliográficos
Autores principales: Perez-Lemus, Gustavo R., Menéndez, Cintia A., Alvarado, Walter, Byléhn, Fabian, de Pablo, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741187/
https://www.ncbi.nlm.nih.gov/pubmed/34995115
http://dx.doi.org/10.1126/sciadv.abj4526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741187/
https://www.ncbi.nlm.nih.gov/pubmed/34995115
http://dx.doi.org/10.1126/sciadv.abj4526

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