O-linked α2,3 sialylation defines stem cell populations in breast cancer

We pursued the hypothesis that specific glycans can be used to distinguish breast cancer stem cells (CSCs) and influence their function. Comparison of CSCs and non-CSCs from multiple breast cancer models revealed that CSCs are distinguished by expression of α2,3 sialylated core2 O-linked glycans. We...

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Detalles Bibliográficos
Autores principales: Walker, Melanie R., Goel, Hira Lal, Mukhopadhyay, Dimpi, Chhoy, Peter, Karner, Emmet R., Clark, Jennifer L., Liu, Haibo, Li, Rui, Zhu, Julie Lihua, Chen, Shuhui, Mahal, Lara K., Bensing, Barbara A., Mercurio, Arthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741191/
https://www.ncbi.nlm.nih.gov/pubmed/34995107
http://dx.doi.org/10.1126/sciadv.abj9513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741191/
https://www.ncbi.nlm.nih.gov/pubmed/34995107
http://dx.doi.org/10.1126/sciadv.abj9513

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