Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving

The poor efficacy of seasonal influenza virus vaccines is often attributed to pre-existing immunity interfering with the persistence and maturation of vaccine-induced B cell responses. We previously showed that a subset of vaccine-induced B cell lineages are recruited into germinal centers (GCs) fol...

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Detalles Bibliográficos
Autores principales: Hoehn, Kenneth B, Turner, Jackson S, Miller, Frederick I, Jiang, Ruoyi, Pybus, Oliver G, Ellebedy, Ali H, Kleinstein, Steven H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741214/
https://www.ncbi.nlm.nih.gov/pubmed/34787567
http://dx.doi.org/10.7554/eLife.70873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741214/
https://www.ncbi.nlm.nih.gov/pubmed/34787567
http://dx.doi.org/10.7554/eLife.70873

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