Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

Gonadotropin-releasing hormone (GnRH) is the primary neuropeptide controlling reproduction in vertebrates. GnRH stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) synthesis via a G-protein-coupled receptor, GnRHR, in the pituitary gland. In mammals, GnRHR lacks a C-terminal c...

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Detalles Bibliográficos
Autores principales: Toufaily, Chirine, Fortin, Jérôme, Alonso, Carlos AI, Lapointe, Evelyne, Zhou, Xiang, Santiago-Andres, Yorgui, Lin, Yeu-Farn, Cui, Yiming, Wang, Ying, Devost, Dominic, Roelfsema, Ferdinand, Steyn, Frederik, Hanyaloglu, Aylin C, Hébert, Terence E, Fiordelisio, Tatiana, Boerboom, Derek, Bernard, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741216/
https://www.ncbi.nlm.nih.gov/pubmed/34939930
http://dx.doi.org/10.7554/eLife.72937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741216/
https://www.ncbi.nlm.nih.gov/pubmed/34939930
http://dx.doi.org/10.7554/eLife.72937

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