Non-targeted characterization of attributes affecting antibody-FcγRIIIa V158 (CD16a) binding via online affinity chromatography-mass spectrometry

Antibodies facilitate targeted cell killing by engaging with immune cells such as natural killer cells through weak binding interactions with Fcγ receptors on the cell surface. Here, we evaluate the binding affinity of the receptor FcγRIIIa V158 (CD16a) for several therapeutic antibody classes, isof...

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Detalles Bibliográficos
Autores principales: Woodall, Daniel W., Dillon, Thomas M., Kalenian, Kevin, Padaki, Rupa, Kuhns, Scott, Semin, David J., Bondarenko, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741291/
https://www.ncbi.nlm.nih.gov/pubmed/34978527
http://dx.doi.org/10.1080/19420862.2021.2004982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741291/
https://www.ncbi.nlm.nih.gov/pubmed/34978527
http://dx.doi.org/10.1080/19420862.2021.2004982

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