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Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway

A balance between bone formation by osteoblasts and bone resorption by osteoclasts is necessary to maintain bone health and homeostasis. As a cancer of plasma cells, multiple myeloma (MM) is accompanied with rapid bone loss and fragility fracture. Bortezomib has been used as a first-line for treatin...

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Detalles Bibliográficos
Autores principales: Fang, Yuepeng, Liu, Yang, Zhao, Zhijian, Lu, Yingjie, Shen, Xu, Zhu, Tianfeng, Hou, Mingzhuang, He, Fan, Yang, Huilin, Zhang, Yijian, Shi, Qin, Zhu, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741347/
https://www.ncbi.nlm.nih.gov/pubmed/35003523
http://dx.doi.org/10.1155/2021/9661200